Weight loss: A 10% drop in weight may result from medication and lifestyle modifications.

 Weight loss: A 10% drop in weight may result from medication and lifestyle modifications.

According to recent studies, weight loss drugs taken in conjunction with lifestyle changes may help people lose 10% of their body weight while also providing important health advantages.

Significant weight loss can be achieved with anti-obesity drugs and lifestyle modifications.

Many Britons reduce their caloric intake to shed those troublesome pounds, but did you know that weight loss drugs paired with lifestyle modifications can help people reach their weight goals?

Recent studies have shown that adopting this strategy, obese patients were able to sustain a weight decrease of around 11% for up to five years.

Data from 428 patients at an academic weight management center were analyzed for the study, which concluded that weight loss of more than 10% has a significant positive impact on health.

"Our real-world study demonstrates that anti-obesity medications along with lifestyle changes can achieve significant weight loss of 10% body weight and that loss is maintained over the long-term," said Michael A. Weintraub, MD, the study's lead author and fellow in the Division of Endocrinology, Diabetes & Metabolism at Weill Cornell Medicine.

"Metabolic abnormalities can be reversed with meaningful benefits in patients with type 2 diabetes, cardiovascular disease, and many other diseases where obesity is the underlying cause," says the study. "If weight loss can be sustained."

"This research can help guide healthcare professionals toward establishing individualized, approachable therapy regimes to aid patients in long-term weight loss," he continued.

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Participants kept their 10.7% average weight decrease.

The obesity medicine specialist offered extra counseling with a licensed dietitian and gave low-glycemic diet and exercise advice to every patient.

The patients also used off-label weight-loss drugs such metformin, phentermine, and topiramate, all of which are FDA-approved.

Participants maintained a weight decrease of 10.7 percent on average over the course of the regimen, which was monitored for around five years.

"In our study, we were amazed by the extent of weight loss obtained and maintained," stated Weintraub. Patients who added anti-obesity drugs lost and maintained an average of 10% of their body weight, or 23 pounds in this cohort, by doing so.

A third of patients, the expert continued, could maintain weight loss of at least 15% over the long term.

Are medicines used to lose weight safe?

If utilized properly, according to Suchitra Rao, MD, a bariatric physician at O'Connor Hospital in San Jose, California,People can safely reach their weight goals with the aid of weight loss medication.

However, she noted that obesity is a chronic, intricate, and recurrent condition. Long-term maintenance of weight loss and prevention of weight regain may necessitate their use.

Healthy eating, regular exercise, getting enough sleep, and stress management are all lifestyle variables that support weight loss.

Although all drugs have possible side effects, according to Minisha Sood, MD, an endocrinologist at Lenox Hill Hospital in New York, the advantages of treating obesity frequently outweigh the dangers.

"Metformin, topiramate, and phentermine have been used successfully and safely for many years," she continued.

According to Sood, these drugs have tolerable side effects and may be stopped quickly if someone encounters them; nevertheless, stopping them can lead to weight gain.

According to the study, overweight and obese persons can lose "substantial" amounts of weight over the long term.

The negative effects of the weight loss medications employed in this trial are rather moderate, according to Weintraub, despite the fact that they will be needed for the rest of one's life.

"Those who make the necessary lifestyle modifications will see a measurable improvement in their quality of life as a result."

The NHS promotes healthy lifestyle changes through food and exercise for people who are seeking to lose weight.

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